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Science

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Imagine a world where we could turn off the genes behind cancer development, progression, and treatment resistance.

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What if we could also deliver the medicines directly to the tumor – with the hope of reducing the terrible side-effects associated with cancer treatment?

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SirnaMed is making that world a reality

Our approach to cancer treatment begins with siRNA, and designing compounds that can silence genes with exquisite specificity. We then pair our siRNAs with chemotherapeutic agents, and co-encapsulate them in one of our two proprietary tumor-targeted polymeric nanoparticle platforms; Combo and siRNA-alone.

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Our nanoparticles are our signature

With our targeted delivery platforms, we hope to achieve direct delivery of the siRNA with or without a chemotherapy drug to the tumors - and not anywhere else, maximizing efficacy and minimizing side-effects.

November 24, 2022

Targeting Xkr8 via nanoparticle-mediated in situ co-delivery of siRNA and chemotherapy drugs for cancer immunochemotherapy

January 4, 2024

Inhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer immunochemotherapy

June, 2024

Knocking down of Xkr8 enhances chemotherapy efficacy through modulating tumor immune microenvironment

Publications

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